Research Articles
The Evolutionary Arms Race: How MHC Class I Genes Shaped Immune Systems from Sharks to Humans
Explore the fascinating evolution of MHC class I molecules across vertebrates and their crucial role in immune system function from sharks to humans.
Unraveling Lupus: How 3D Genome Maps Reveal Hidden Genetic Secrets
Discover how promoter connectome mapping in follicular helper T cells reveals novel genetic mechanisms behind systemic lupus erythematosus and potential therapeutic targets.
The Secret Keeper of Pregnancy: How HLA-E Shields Life From Immune Attack
Discover how HLA-E gene expression in trophoblast cells creates immune tolerance during pregnancy through epigenetic mechanisms.
Unmasking the Invisible Army: The Precision Art of Counting Our Body's Defenders
Discover how scientists detect and quantify antibodies using ELISA technology to diagnose diseases, develop vaccines, and understand immune responses.
The Social Ape's Secret: How Bonobo Immunity Thrives on Diversity
Discover how bonobos maintain immune system diversity with just three functional types of MHC-B genes, revealing an evolutionary survival strategy.
The Silent Symphony: How Physiology Orchestrates Our Health and Future
Explore how physiology serves as the foundation of modern medicine and biomedical innovation through recent discoveries in immune regulation and microRNA.
Beyond DNA: How Epigenetics Steers Our Innate Immune System
Discover how epigenetic regulation enables trained immunity in our innate immune system, rewriting immunology textbooks and opening new therapeutic frontiers.
The Body's Friendly Fire: How Scientists Found the Brakes on Our Cellular Defenders
Discover how functional genomics uncovered the master switches controlling our immune system's powerful oxidative burst mechanism.
The Chicken Cytokine Mystery: How a Mislabeled Molecule Rewrote Avian Immunology
Discover how scientists solved the mystery of the missing chicken cytokine and reclassified MGF as G-CSF/CSF3, rewriting our understanding of avian immunity.
The T-bet Enigma: When Molecular Keys Fit Every Lock But Don't Always Turn
Exploring the paradoxical behavior of T-bet transcription factor in immune cells - universal binding with context-dependent functional effects